M-PVA Magnetic Beads

chemagen started it's business with the development, functionalisation and production of magnetic particles based on polyvinyl alcohol. We call them M-PVA Magnetic Beads. They represent a new class of particles and allow applications in nearly every scientific or industrial field.

The surfaces of the M-PVA beads can be functionalized with many different groups and modified with individually tunable loadings. The figure on the left side shows a selection of functionalized, activated and "Ready-to-Use" M-PVA Magnetic Beads offered by chemagen as standard.

The potential of these functionalizations enables extensive and simple modifications with regard to any separation problem. The following listings and the related pages should give an overview about the possibilities.

Molecular biology and biochemistry

  • unspecific isolation of nucleic acids, e.g. for use in PCR
  • automated isolation and purification of DNA (analysis diagonstics of genes)
  • detection or isolation of specific nucleic acid sequences, e.g. mRNA
  • affinity purification of proteins
    (e.g. antibodies, lectins, DNA/RNA binding proteins)
  • preparation of molecule libraries (e.g. oligonucleotides, DNA, RNA or proteins, but also libraries with smaller molecules) by use of combinatorial strategies
  • screening and selection of libraries

Medical diagnostics

  • cell separation and cell standardization
  • enzyme immunoassay (determination of pathogenic substances)
  • antigen or antibody detection by indirect agglutination
  • carriers for drug targeting during specialized use of drugs, e.g. in cancer therapy
  • removal of pathogenic substances from blood