Press Release
New Product for the Isolation of Total RNA from Stabilized Blood
Worcester, July 28th 2010. chemagen launches its first chemagic Kit for the isolation of total RNA from stabilized blood. The chemagic Total RNA Kit special is designed for the automated isolation of total RNA from 2.5 ml blood collected in PAXgeneTM RNA tubes with the chemagic Magnetic Separation Module I (chemagic MSM I).
The chemagic MSM I can process up to 24 of these blood samples in parallel. Typical yields are 7 - 16 µg total RNA. Starting with a kit for the isolation of total RNA from stabilized blood, the launch of a total RNA kit dedicated for RNA extraction from cells and tissue will follow soon.
chemagen offers several other kits for the isolation of different types of RNA. Viral RNA can be isolated from different clinical sample materials with the chemagic Viral DNA/RNA Kits or the chemagic Viral NA/gDNA Kits. Messenger RNA can be easily separated with the chemagic mRNA Kits for automated or manual use.
About chemagen AG
chemagen is a key player in the field of automated nucleic acid isolation. The purification of DNA, RNA, or viral DNA/RNA is facilitated through chemagen’s proprietary M-PVA Magnetic Bead technology. chemagen’s high performance instrument is the chemagic MSM I. It enables the automated separation of nucleic acids from sample volumes between 10 μl 10 ml. Kits for sample materials such as blood, serum/plasma, tissue, saliva, buccal swabs, amniotic fluid or feces are also available. With the chemagic Prepito, chemagen offers a benchtop walk-away instrument relying upon the proven separation technology for up to 1000 µl sample material and 1 – 12 samples in parallel.
Outstanding robustness, minimal hands on time and fast automated applications translate to the highest throughput and flexibility of your laboratory workflow.
Find further information on www.chemagen.com
Contact:
chemagen USA, Inc.
Stan Klein
General Manager
67 Millbrook Street
Worcester, MA 01606
USA
Swine Flu – Fast and Reliable Isolation of the Viral RNA
Baesweiler, September 7th 2009. The growing amount of suspicious cases for swine flu in addition to the other daily samples forces diagnostic laboratories to react. They need a reliable, time saving solution to cope with a daily throughput of up to 500 additional samples per day. Besides the rising number of samples, the incoming sample material used for different diagnostic requests is very heterogeneous. Processing stool, plasma, swabs and urine in parallel is almost the only way to deal with the huge amount of daily samples. But this variety of sample materials makes it more or less impossible to automate the crucial step of nucleic acid isolation. However chemagen offers a very flexible solution to solve this problem – the chemagic Magnetic Separation Module I.
The chemagic Magnetic Separation Module I (chemagic MSM I) performs automated nucleic acid isolation within one hour. Viral RNA of 96 nasal swabs can be extracted in parallel. “We couldn’t cope with 500 additional samples per day without our chemagic MSM I.” says Dr. Andreas Lindauer, sYnlab Molecular Biology, Weiden, Germany.
chemagic Viral Kits: One for All
“We place stool suspensions, blood, plasma, serum and urine samples on a 96 well plate and isolate the nucleic acids with a generic chemagen protocol. That saves a lot of time. No cross contaminations occurred so far.” Dr. Michael Weizenegger, Labor Limbach, Heidelberg, Germany describes one of the main advantages of the chemagic MSM I: the ability to process various sample materials with one kit – the chemagic gDNA/Viral NA Kit special, which is dedicated to the use with the chemagic MSM I.
Highest Flexibility in Sample Volumes
Due to three chemagic Rod Heads – exchangeable within minutes – the chemagic MSM I is very flexible. Corresponding to standard well plates the chemagic MSM I can be equipped with a chemagic 12, 24 or 96 Rod Head. Thus sample volumes from 10 µl – 10 ml can be processed easily using only one instrument. The chemagic 96 Rod Head with 96 thin steel needles is destined for high throughput applications. Processing 96 samples with the typical volume of 200 µl to extract pathogen DNA and RNA takes only 60 minutes.
The chemagic Prepito
“Sometimes late in the afternoons we get a few urgent samples that we don’t want to process manually, in this case the chemagic Prepito is the perfect system. It can process up to 12 samples with the same efficiency as the chemagic MSM I.” says Dipl.-Biol. Christian Klos (sYnlab Weiden). This small benchtop solution facilitates NA isolation from 10 µ – 600 µl. The chemagic Prepito uses the same separation technology as the chemagic MSM I.
The chemagic Separation Technology
chemagen’s core competence is the development and production of magnetic particles for nucleic acid isolation. These proprietary M-PVA Magnetic Beads have a high affinity to nucleic acids. Both chemagic isolation platforms use this unique separation principle: A strong electromagnet magnetizes steel needles of the chemagic Rod Heads, covered with disposable tips to avoid contamination. M-PVA Magnetic Beads are attracted by these magnetized needles. Due to their DNA/RNA binding capacity, the Magnetic Beads transport the nucleic acids from one vessel to another during the whole isolation process. Lysis, mixing, binding and elution are realized through the patented rotation of the needles when the magnet is off. This technology does not lead to DNA shearing and supports an efficient binding of nucleic acids to the beads.
New subsidiary in the United States
In July 2009 chemagen AG has founded a subsidiary in the USA. Based on several years of experience in the field of Human Genetics, HLA Typing, Blood Banking and Pathogen Diagnostics the customers of chemagen USA, Inc. will benefit from this knowledge. chemagen offers highly qualified technical support and never hesitates to offer a customized solution.
chemagen’s Distribution Channels
chemagen distributes its products directly or through one of the 19 distributors all over the world. The entire list of chemagen distributors can be found at www.chemagen.com/distributors.html. Most partners decided for the chemagic automation to complete their portfolio offering solutions for human diagnostics. The extracted DNA/RNA is ready to use for many downstream applications such as HLA Typing, Real-Time PCR, Sequencing or Hybridisation Assays. chemagen is always looking for new distribution partners in countries that are yet not covered by their distribution network.
For further pictures and information visit www.chemagen.com.
About chemagen AG
chemagen is a key player in the field of automated nucleic acid isolation. The purification of DNA or viral DNA/RNA is facilitated through chemagen’s proprietary M-PVA Magnetic Bead technology. chemagen’s high performance instrument is the chemagic Magnetic Separation Module I (chemagic MSM I). It enables automated separation of nucleic acids from sample volumes between 10 µl – 10 ml. Available kit applications include sample materials such as blood, serum/plasma, tissue, saliva, buccal swabs, amniotic fluid or feces. With the chemagic Prepito, chemagen offers a benchtop walk-away instrument relying upon the proven separation process for up to 600 µl blood and 1 - 12 samples in parallel.
Outstanding robustness, minimal hands on time and fast automated applications translate to the highest throughput and flexibility of your laboratory workflow.
Find further information at www.chemagen.com
Contact:
Dr. Ulla Krueppel
International Marketing
chemagen Biopolymer-Technologie AG
Arnold-Sommerfeld-Ring 2
D – 52499 Baesweiler
Fon: 0049-2401-805500
Mail: info@chemagen.de
chemagic 8 – a lab in a box
Baesweiler, March 30th 2009, the chemagen AG, Germany, introduces the chemagic 8, a customized solution for the entire laboratory workflow process. This particular lab in a box facilitates primary sample handling via Nucleic Acid isolation to diagnostics and storage with minimized hands on time in a fully automated way – that´s the chemagic AID.
The chemagic 8 combines 8 different features in an outstanding manner. The entire laboratory workflow processes such as primary sample handling via Nucleic Acid isolation to diagnostics and storage are fully automated. Due to minimized hands on time cross contaminations are almost impossible.
Its modular setup makes the chemagic 8 extraordinary flexible. Extensions, integrations and updates can be easily facilitated due to 8 axes that allow 360° movements of this prototype. In-process sample loading enables operating day and night at seven days/week. Once the primary probe is placed in, the chemagic AID takes over all subsequent duties.
The 8 main features at a glance:
1. Automated
- From primary sample via NA preparation to diagnostics and storage
2. Modular
- Extensions, integrations and updates can be easily facilitated
3. Reliable
- Approved technologies are included such as the chemagic Magnetic Separation Module I
- Reproducible results
4. Save
- No cross contamination
- Barcode reading prevent sample mix-up
5. Fast
- Variable speed
- Time consuming processes are done automatically
6. Efficient
- Cost effective
7. Flexible
- 8 axes allow 360° movement
8. 24/7
- Operates day and night (24 h and 7 days/week)
- In-process sample loading possible
- Minimized hands on time
- Maximum throughput
These particular 8 features are visualized in an animated film that can be ordered here or via download at www.chemagen.de/147.80.html.
The chemagic 8 was developed as customized solution in collaboration with ABBIS bio process automation. Thus this particular prototype is currently under construction. More or other features can be realized due to the requirements of the laboratory workflow.
About chemagen AG
chemagen Biopolymer-Technologie AG, located in Germany, is a key player in the field of automated nucleic acid isolation. The purification of DNA or viral DNA/RNA is facilitated through chemagen’s proprietary M-PVA Magnetic Bead technology. chemagen’s high performance instrument is the chemagic Magnetic Separation Module I (chemagic MSM I). It enables automated separation of nucleic acids from sample volumes between 10 µl – 10 ml. Available kit applications include sample materials such as blood, serum/plasma, tissue, saliva, buccal swabs, amniotic fluid or faeces. With the chemagic Prepito, chemagen offers a benchtop walk-away instrument relying upon the proven separation process for up to 600 µl blood and 1 - 12 samples in parallel.
Outstanding robustness, minimal hands on time and fast automated applications translate to the highest throughput and flexibility of your laboratory workflow.
Find further information at www.chemagen.com
Contact:
Dr. Ulla Krueppel
International Marketing
chemagen Biopolymer-Technologie AG
Arnold-Sommerfeld-Ring 2
52499 Baesweiler
Tel: 0049-2401-805513
ulla.krueppel@chemagen.de
chemagen´s first CE certified product
Baesweiler, February 24th 2009, chemagen Biopolymer-Technologie AG, Germany, announces its first CE certified Plasma Kit, which facilitates an automated preparation of DNA/RNA from 2 ml plasma samples. 1 - 24 samples can be processed in parallel using the chemagic Separation Module I and within 60 minutes the DNA/RNA is then ready to use for your in vitro Diagnostic applications.
The chemagic Plasma D2.0 Kit is now CE certified in compliance with EU IVD Directive 98/79/EC*. This mark particularly helps European clinical laboratories to perform nucleic acid preparation from plasma to facilitate compliance with IVD directives in their countries. The chemagic Plasma D2.0 Kit is intended for automated nucleic acid preparation from up to 2 ml serum or plasma. 24 samples can be processed at once in 60 minutes using chemagen´s robust and reliable automation – the Magnetic Separation Module I (MSM I). This machine was developed for automated nucleic acid isolation based on chemagen´s proprietary magnetic bead technology.
The principle is very efficient: Nucleic acids from serum/plasma bind to the surface of the patented Polyvinyl Alcohol (PVA) particles and can be further isolated automatically using the 24 magnetized rods of the chemagic 24 Rod Head. The DNA/RNA can be eluted either in TE, 10 mM Tris-HCl pH 8.0 or water. These high quality nucleic acids are ready to use for many downstream applications or disposed to long term storage.
Blood donation services and plasma fractionation facilities might be highly interested in this particular CE certified kit. The chemagic Plasma D2.0 Kit facilitates the viral screening of blood products. The validation of your entire diagnostic process is now simplified by using the chemagic Plasma D2.0 Kit for sample preparation. Additional CE IVD certified kits are currently in process.
About chemagen AG
chemagen Biopolymer-Technologie AG, located in Germany, is a key player in the field of automated nucleic acid isolation. The purification of DNA or viral DNA/RNA is facilitated through chemagen’s proprietary M-PVA Magnetic Bead technology. chemagen’s high performance instrument is the chemagic Magnetic Separation Module I (chemagic MSM I). It enables automated separation of nucleic acids from sample volumes between 10 µl – 10 ml. Available kit applications include sample materials such as blood, serum/plasma, tissue, saliva, buccal swabs, amniotic fluid or faeces. With the chemagic Prepito, chemagen offers a benchtop walk-away instrument relying upon the proven separation process for up to 600 µl blood and 1 - 12 samples in parallel.
Outstanding robustness, minimal hands-on-time and fast automated applications translate to the highest throughput and flexibility of your laboratory workflow.
Find further information at www.chemagen.com
Contact:
Dr. Ulla Krueppel
International Marketing
chemagen Biopolymer-Technologie AG
Arnold-Sommerfeld-Ring 2
52499 Baesweiler
Tel: 0049-2401-805513
ulla.krueppel@chemagen.de
*according to annex III of directive 98/79/EC
